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ISOLATION AND STRUCTURE ELUCIDATION OF NOVEL OLIGOSACCHARIDE FROM GOAT MILK
Milk is a primary dynamic biological fluid responsible for proper growth and development of mammalian neonates. Besides the other regular constituents it has oligosaccharides in it which are responsible for anti-tumor, anti-cancer, anti-pathogenic, anti-inflammatory, anti-coagulant, anti-complementary, antigenic, hypoglycemic, immunological, immunostimulant and prebiotic activities. Goat milk oligosaccharides have anti-inflammatory properties and are involved in the repairing process after a dextran sodium sulphate-induced colitis.
In the present studies, we have selected the goat milk for its oligosaccharide contents for which it was processed by modified Kobata and Ginsburg method followed by the HPLC and CC techniques. The structure of the isolated oligosaccharide was elucidated by chemical transformation, chemical degradation, 1H, 13C, 2D-NMR (COSY, TOCSY and HSQC) and mass spectrometry as under.