Abstract
RELATIONSHIP BETWEEN MATERNAL ANAEMIA AND RISK OF PREECLAMPSIA
Heba Alshardoub*, Prof. Maisoon Dayoub and Prof. Basel Mohamad
ABSTRACT
Background: Preeclampsia is among the leading causes of morbidity and mortality worldwide, affecting approximately 4.6% of all pregnancies. In contrast, anemia during pregnancy significantly increases the risk of pre-eclampsia as well as fetal complications. However, the importance of this association is still inconclusive, and it is suggested that the increased risk of pre-eclampsia be associated with the severity of iron deficiency, and not only with the presence of anemia. Objective: To determine the prevalence of iron deficiency anemia among pre-eclampsia patients among pregnant women attending the obstetrics department at Tishreen University Hospital, to extrapolate the relationship between them and compare it with the control sample. Materials and Methods: This prospective study included 120 pregnant women in the third trimester of pregnancy who attended the outpatient department or admissions in the Department of Obstetrics and Gynecology at Tishreen University Hospital, Latakia, during the period between March 2022- March 2023. Pregnant women were followed up until the end of their pregnancy to determine outcomes. The participants in the research were classified into two groups: a control group that included healthy pregnant women, and a case group that included pregnant women with pre-eclampsia. Their iron deficiency anemia was investigated by measuring hemoglobin, hematocrit, iron, and serum binding capacity. Results: The average age of the research sample patients was 26 ? 5.2 years. We did not find statistically significant differences between the two research samples in terms of basic characteristics or the number of pregnancies, deliveries, and miscarriages. 0.001). And we had a statistical relationship between the severity of preeclampsia and the severity of serum iron deficiency (with iron deficiency p = 0.002, and with severe serum iron deficiency p = 0.003). Conclusion: Pre-eclampsia patients are exposed to anemia with a rate of approximately twice that of pregnant women who do not suffer from pre-eclampsia, and a deficiency of serum iron by more than 4 times, and the more severe the iron deficiency, the more severe the pre-eclampsia.
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