Abstract
MALIGNANT PARAGANGLIOMA OF NECK: A CASE REPORT AND REVIEW OF LITERATURE
*Mir Ruquaya, M.B.B.S, DNB, Singh Vikram P., M.B.B.S, M.S.
ABSTRACT
Malignant paragangliomas are rare tumors of head and neck which are composed of sustenacular and chief cells arranged in Zellballen pattern. Malignant paragangliomas (PGS) are confirmed by presence of cells in lymph nodes or by presence of distant metastasis. PGs of head and neck originate in parasympathetic autonomic nervous system ganglia and are typically non secretory and benign in nature compared to thoracic and abdominal PGS which arise from sympathetic autonomic nervous system and are usually functional and aggressive in behavior. Because of rarity of tumor there are no clinical trials to guide on the management of these tumors.
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