Abstract
EVALUATION OF EFFICIENCY OF SPR-BASED BIOSENSOR AND ZnO PHOTOLUMINESCENT BIOSENSOR IN THE ANLYSYS OF BIOGENIC POLYAMINES
M. P. Prilutskiy, N. F. Starodub* and O. P. Taran
ABSTRACT
Summary: In this research it was demonstrated the efficiency of the biosensors based on the different principles at the detection of the biogenic amines which are as informative elements at the diagnostic of the cancer events including development of the breast cancer. It was compared two type of the optical devices namely based on the surface plasmon resonance (SPR) and on the photoluminescence of the ZnO nanostructures. Both types of the biosensors could able to detect such low molecular agents as polyamines in model solution at the concentration from 10 to 100 ng/ml. Nevertheless SPR-based biosensor showed better results than ZnO biosensor at the detecting as low and high concentrations of polyamines. In particular, the differences in the analyse efficiency at the determination of the above indicated concentrations between the used biosensors was in range from 14% to 30%. In spite of this data it was demonstrated that ZnO biosensor also may be used for estimation of level of polyamines at the cancer diagnostics.
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